Auto-immune haemolytic anaemia (AIHA) is an auto-immune disorder where the body produces antibodies against its own red blood cell antigens, resulting in destruction of RBCs and manifested as anaemia. Previously cases having AIHA with immune thrombocytopenia (ITP) and AIHA with alopecia areata have been reported. Here a case of AIHA, immune thrombocytopenia and alopecia totalis is reported.