Increase in the level of carbon dioxide and depletion of ozone layer in the atmosphere cause global warming –a serious threat to mankind. Global warming and air pollution are associated with many frateful diseases for concern. Air pollution had decreased average life expectancy by about 5.5 years. Although Beijing has the worst pollution index, Delhi and Kolkata are not far away. The primary causes of such pollution in cities and urban areas are lack of clearly defined standards for vehicle emission control. Monitoring pollution in the industries is a must for developed and developing countries. Fuel standards must be aggressively monitored. The world must resort to renewable sources of energy such as solar and wind power. Deforestation is another area which triggers global warming and pollution. Natural disasters like flood, earthquake and draughts are indirect effects of global warming. The medical fraternity as a part in the society should have a big role to play in making globe free of all disasters if any in the future.